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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PI15 All Species: 35.15
Human Site: S235 Identified Species: 85.93
UniProt: O43692 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43692 NP_056970.1 258 29065 S235 P C S S C P P S Y G G S C T D
Chimpanzee Pan troglodytes XP_525333 253 28490 S231 P C S S C P P S Y Q G S C N S
Rhesus Macaque Macaca mulatta XP_001087136 258 29077 S235 P C S S C P P S Y G G S C T D
Dog Lupus familis XP_544132 258 28969 S235 P C S A C P P S Y G G S C T D
Cat Felis silvestris
Mouse Mus musculus Q8BS03 258 29132 S235 P C S S C P P S Y G G A C T D
Rat Rattus norvegicus NP_001100387 258 29251 S235 P C S S C P P S Y G G A C T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515857 267 29619 K232 P C S A C P S K Y G G R C K S
Chicken Gallus gallus Q98ST6 258 29220 S235 P C S A C P P S Y G G S C T D
Frog Xenopus laevis Q3KPV7 258 29176 S235 P C S A C P P S Y G G S C S D
Zebra Danio Brachydanio rerio Q7T141 260 29326 S237 P C S M C P P S Y G G S C S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.5 99.6 98 N.A. 93.4 91.4 N.A. 52.8 90.3 79 73.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 74 99.6 99.2 N.A. 94.9 94.5 N.A. 68.9 93 89.9 84.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 100 93.3 N.A. 93.3 93.3 N.A. 60 93.3 86.6 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 100 100 N.A. 100 100 N.A. 66.6 100 100 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 40 0 0 0 0 0 0 0 20 0 0 0 % A
% Cys: 0 100 0 0 100 0 0 0 0 0 0 0 100 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 90 100 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 100 0 0 0 0 100 90 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 100 50 0 0 10 90 0 0 0 70 0 20 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _